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It targets the same two receptors as Mounjaro, GLP-1 and GIP, but adds a third: the glucagon receptor

"A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Are Overweight (TRIUMPH-1)." NCT05929066

The medication lowers blood sugar by increasing insulin production and lowering glucagon secretion, curbs appetite and allows people to lose weight by eating less

Diarrhea, constipation, vomiting, abdominal pain, and decreased appetite round out the typical complaints

J Zhejiang Univ Sci B

This brief pause allows the medication to disperse slightly in the tissue and prevents medication from leaking back through the needle track when you withdraw